| Psoriasis is a visible manifestation of the skin's defense against micro-organisms. | |
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MedLine Citation:
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PMID: 8063999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The recent discovery that human epidermal cells themselves make and secrete the components necessary for activation of the alternative complement pathway appears to provide an explanation for how human skin is ordinarily able to avoid colonization by molds and other organisms. It also helps clarify the mechanisms underlying clinical and laboratory findings seen in chronic mucocutaneous candidiasis, dandruff, and psoriasis. Psoriasis seems best explainable as a visible, late stage of the inflammatory sequelae of activation of the alternative complement pathway in the epidermis. |
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Authors:
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E W Rosenberg; P W Noah; R B Skinner |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: The Journal of dermatology Volume: 21 ISSN: 0385-2407 ISO Abbreviation: J. Dermatol. Publication Date: 1994 Jun |
Date Detail:
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Created Date: 1994-09-20 Completed Date: 1994-09-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 375-81 Citation Subset: IM |
Affiliation:
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Department of Medicine (Dermatology), University of Tennessee College of Medicine, Memphis. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Complement Activation Dermatomycoses / immunology* Fungi / immunology* Humans Immunity Psoriasis / immunology*, microbiology Skin / immunology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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