| Psoriasis in association with prolactinoma: three cases. | |
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MedLine Citation:
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PMID: 11069474 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report three women with plaque-type psoriasis in whom increase in severity and extent of the skin lesions correlated with the development of a prolactinoma. In all three patients, administration of bromocriptine, a dopamine agonist that suppresses the secretion of prolactin, improved the therapeutic response of the psoriasis. To our knowledge, there are no reports of an association between psoriasis and prolactinoma. In recent years it has become apparent that prolactin plays an important part in the immune reactions and exerts a proliferative effect on human keratinocytes. We, therefore, discuss the part that prolactin may play in the pathogenesis of psoriasis. |
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Authors:
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M Sánchez Regaña; P Umbert Millet |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The British journal of dermatology Volume: 143 ISSN: 0007-0963 ISO Abbreviation: Br. J. Dermatol. Publication Date: 2000 Oct |
Date Detail:
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Created Date: 2000-11-20 Completed Date: 2000-11-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0004041 Medline TA: Br J Dermatol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 864-7 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Hospital Sagrado Corazón, University of Barcelona, C/París 83-87 5th floor, 08029 Barcelona, Spain. ez.reg@teleline.es |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Paraneoplastic Syndromes / etiology* Pituitary Neoplasms / complications* Prolactin / physiology Prolactinoma / complications* Psoriasis / etiology* |
| Chemical | |
Reg. No./Substance:
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9002-62-4/Prolactin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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