Document Detail

Psoriasis in association with prolactinoma: three cases.
MedLine Citation:
PMID:  11069474     Owner:  NLM     Status:  MEDLINE    
We report three women with plaque-type psoriasis in whom increase in severity and extent of the skin lesions correlated with the development of a prolactinoma. In all three patients, administration of bromocriptine, a dopamine agonist that suppresses the secretion of prolactin, improved the therapeutic response of the psoriasis. To our knowledge, there are no reports of an association between psoriasis and prolactinoma. In recent years it has become apparent that prolactin plays an important part in the immune reactions and exerts a proliferative effect on human keratinocytes. We, therefore, discuss the part that prolactin may play in the pathogenesis of psoriasis.
M Sánchez Regaña; P Umbert Millet
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  143     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2000-11-20     Completed Date:  2000-11-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  864-7     Citation Subset:  IM    
Department of Dermatology, Hospital Sagrado Corazón, University of Barcelona, C/París 83-87 5th floor, 08029 Barcelona, Spain.
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MeSH Terms
Paraneoplastic Syndromes / etiology*
Pituitary Neoplasms / complications*
Prolactin / physiology
Prolactinoma / complications*
Psoriasis / etiology*
Reg. No./Substance:

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