Document Detail

Psoriasis Vulgaris Caused by Ceramic Inserts Used in Total Hip Replacement.
MedLine Citation:
PMID:  23149205     Owner:  NLM     Status:  Publisher    
Background:Ceramics are inorganic nonmetallic materials and are used as bioinert components in joint replacement surgeries. Ceramics are known to be low allergenic. We experienced a ceramic-induced psoriasis.Objective:We report a first case of possible ceramic-induced psoriasis caused by a ceramic insert.Methods:A 55-year-old female received an implanted ceramic-on-ceramic total hip replacement for osteoarthritis of the right hip joint. Following surgery, she developed psoriatic lesions, which continued for 10 years. We suspected that psoriasis was caused by a ceramic insert and removed it surgically.Results:When the ceramic insert was replaced with a polyethylene-on-metal hip joint, the psoriatic lesions completely disappeared.Conclusion:The pathogenesis of psoriasis is still an enigma, although deregulation of nuclear factor κB signaling and resulting abnormal cytokine secretion are speculated to be involved. Ceramics may affect these signaling events and cause the onset of psoriasis.
Fujio Higuchi; Daisuke Tsuruta; Yumiko Ishibashi; Kazuko Imamura; Tokiko Shimoyama; Takahiro Ookawa; Shinichiro Kume; Shiro Yoshida; Masafumi Gotoh; Akio Noda; Toshie Mori; Takahiro Hamada; Norito Ishii; Teruki Dainichi; Hiromi Kobayashi; Kensei Nagata; Takashi Hashimoto
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Publication Detail:
Journal Detail:
Title:  Journal of cutaneous medicine and surgery     Volume:  16     ISSN:  1203-4754     ISO Abbreviation:  J Cutan Med Surg     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9614685     Medline TA:  J Cutan Med Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  448-450     Citation Subset:  -    
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