Document Detail


Psoriasiform eruption triggered by a dipeptidyl peptidase IV inhibitor.
MedLine Citation:
PMID:  22309337     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Psoriatic patients have a higher prevalence of diabetes mellitus type 2 (DM). Since dipeptidyl peptidase IV (DPP-IV) dysregulation is present in DM and psoriasis, DPP-IV inhibitors have been proposed as therapeutic agents for both conditions. We report a psoriasiform eruption induced by sitagliptin, a DPP-IV inhibitor. The role of DPP-IV in the pathogenesis of DM is well established; however data on psoriatic patients is contradictory. More studies are required to elucidate the effect of DPP-IV inhibitors and their relationship with DM and psoriasis.
Authors:
Albert Mas-Vidal; Jorge Santos-Juanes; Altea Esteve-Martinez; Luis Caminal-Montero; Pablo Coto-Segura
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Publication Detail:
Type:  Journal Article     Date:  2011-06-13
Journal Detail:
Title:  The Australasian journal of dermatology     Volume:  53     ISSN:  1440-0960     ISO Abbreviation:  Australas. J. Dermatol.     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-02-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0135232     Medline TA:  Australas J Dermatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  70-2     Citation Subset:  IM    
Copyright Information:
© 2011 The Authors. Australasian Journal of Dermatology © 2011 The Australasian College of Dermatologists.
Affiliation:
Department of Dermatology Department of Internal Medicine, University Hospital of Asturias, Oviedo, Spain.
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