Document Detail

Psoralens and ocular effects in humans.
MedLine Citation:
PMID:  6531036     Owner:  NLM     Status:  MEDLINE    
The safety of psoralen photochemotherapy (PUVA) in relation to the eye has been an area of research at the Washington Hospital Center for the last 6 years. Our studies indicate that, with proper shielding of the eye, safety for acute lenticular damage can be established. However, the potential for cataract formation from low-dose, long-term ambient UVA exposure is not known. The guidelines for proper shielding of the eye with PUVA therapy have been established and are enumerated in the text. Our studies on 68 patients for an average length of 4 years and 7 months while they received PUVA have established that the rate in the development of cataracts in treated patients had not increased as compared with the Framingham Eye Study.
W B Glew; T P Nigra
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  National Cancer Institute monograph     Volume:  66     ISSN:  0083-1921     ISO Abbreviation:  Natl Cancer Inst Monogr     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-05-14     Completed Date:  1985-05-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0216026     Medline TA:  Natl Cancer Inst Monogr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  235-9     Citation Subset:  IM    
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MeSH Terms
Cataract / chemically induced
Eye / drug effects*
PUVA Therapy / adverse effects*
Photochemotherapy / adverse effects*
Radiation Protection

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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