| Pseudorabies virus latency: restricted transcription. | |
| | |
MedLine Citation:
|
PMID: 2155596 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cloned pseudorabies virus (PRV) sequences representing over 80% of the viral genome were radiolabeled and individually hybridized to nucleic acid in the trigeminal ganglia of acutely and latently infected swine. In acutely infected animals, all cloned probes hybridized to PRV RNA and DNA. In contrast, during latency transcription was found to be limited to a selected region, corresponding to the IE gene, analogous to that of two other alpha-herpesviruses. Viral DNA was not detected in latently infected neurons by in situ hybridization. |
| | |
Authors:
|
J R Lokensgard; D G Thawley; T W Molitor |
Related Documents
:
|
2216776 - Non-radioactive labeling of rna transcripts in vitro with the hapten digoxigenin (dig);... 8772186 - Hybridization of two oligodeoxynucleotides to both strands of an rna hairpin structure ... 8133786 - Analysis of micronuclei induced in mouse early spermatids by mitomycin c, vinblastine s... 22593716 - Characterization of edna from the clinical strain acinetobacter baumannii aiims 7 and i... 2005916 - Introduction of exogenous dna into chlamydomonas reinhardtii by electroporation. 22484486 - Increased mobility of double-strand breaks requires mec1, rad9 and the homologous recom... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
|
Title: Archives of virology Volume: 110 ISSN: 0304-8608 ISO Abbreviation: Arch. Virol. Publication Date: 1990 |
Date Detail:
|
Created Date: 1990-04-06 Completed Date: 1990-04-06 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7506870 Medline TA: Arch Virol Country: AUSTRIA |
Other Details:
|
Languages: eng Pagination: 129-36 Citation Subset: IM |
Affiliation:
|
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals DNA, Viral / genetics Gene Expression Regulation, Viral Genes, Viral Herpesvirus 1, Suid / genetics* Molecular Sequence Data Neurons / microbiology Nucleic Acid Hybridization Pseudorabies / genetics, microbiology RNA, Viral / genetics Restriction Mapping Swine Swine Diseases / genetics, microbiology Transcription, Genetic* |
| Chemical | |
Reg. No./Substance:
|
0/DNA, Viral; 0/RNA, Viral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Role of DNA topoisomerase I in the replication of herpes simplex virus type 2.
Next Document: Isolation of HHV-6-related virus from children affected by infectious syndrome.