| The Pseudomonas syringae effector protein HopZ1a suppresses effector-triggered immunity. | |
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MedLine Citation:
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PMID: 20636323 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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*The Pseudomonas syringae pv syringae type III effector HopZ1a is a member of the HopZ effector family of cysteine-proteases that triggers immunity in Arabidopsis. This immunity is dependent on HopZ1a cysteine-protease activity, and independent of known resistance genes. We have previously shown that HopZ1a-triggered immunity is partially additive to that triggered by AvrRpt2. These partially additive effects could be caused by at least two mechanisms: their signalling pathways share a common element(s), or one effector interferes with the response triggered by the other. *Here, we investigate the molecular basis for the partially additive effect displayed by AvrRpt2- and HopZ1a-triggered immunities, by analysing competitive indices, hypersensitive response and symptom induction, PR-1 accumulation, expression of PR genes, and systemic acquired resistance (SAR) induction. *Partially additive effects between these defence responses require HopZ1a cysteine-protease activity, and also take place between HopZ1a and AvrRps4 or AvrRpm1-triggered responses. We establish that HopZ1a-triggered immunity is independent of salicylic acid (SA), EDS1, jasmonic acid (JA) and ethylene (ET)-dependent pathways, and show that HopZ1a suppresses the induction of PR-1 and PR-5 associated with P. syringae pv tomato (Pto)-triggered effector-triggered immunity (ETI)-like defences, AvrRpt2-triggered immunity, and Pto or Pto (avrRpt2) activation of SAR, and that suppression requires HopZ1a cysteine-protease activity. *Our results indicate that HopZ1a triggers an unusual resistance independent of known pathways and suppresses SA and EDS1-dependent resistance. |
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Authors:
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Alberto P Macho; Carlos M Guevara; Pablo Tornero; Javier Ruiz-Albert; Carmen R Beuzón |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-15 |
Journal Detail:
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Title: The New phytologist Volume: 187 ISSN: 1469-8137 ISO Abbreviation: New Phytol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9882884 Medline TA: New Phytol Country: England |
Other Details:
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Languages: eng Pagination: 1018-33 Citation Subset: IM |
Affiliation:
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Instituto de Hortofruticultura Subtropical y Mediterranea, Universidad de Málaga-Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC), Depto Biología Celular, Genética y Fisiología, Campus de Teatinos, Málaga E-29071, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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