| Pseudomonas infections in children with human immunodeficiency virus infection. | |
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MedLine Citation:
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PMID: 1528645 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirteen bacteremias and 25 nonbacteremic infections caused by Pseudomonas spp. occurred in 22 of 236 children with human immunodeficiency virus infection with a rate of infection of 0.098 (bacteremia, 0.030) per patient year. Four patients were neutropenic (less than 500/microliters). Central venous catheter (CVC)-related infections were most frequent (n = 20) followed by otitis externa (n = 6) and pneumonia (n = 5). Pseudomonas aeruginosa was the most common isolate and caused both CVC-related and CVC-unrelated infections, whereas other Pseudomonas spp. and Xanthomonas maltophilia were almost exclusively associated with CVC-related infections. The children who received appropriate therapy had a favorable outcome. In 7 CVC-related infections (35%) the catheter was removed. Pseudomonas spp. are of increasing importance in human immunodeficiency virus-infected children causing significant morbidity and increased hospitalization. These infections may be life-threatening if appropriate therapy is not vigorously initiated. |
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Authors:
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E Roilides; K M Butler; R N Husson; B U Mueller; L L Lewis; P A Pizzo |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Pediatric infectious disease journal Volume: 11 ISSN: 0891-3668 ISO Abbreviation: Pediatr. Infect. Dis. J. Publication Date: 1992 Jul |
Date Detail:
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Created Date: 1992-10-22 Completed Date: 1992-10-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8701858 Medline TA: Pediatr Infect Dis J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 547-53 Citation Subset: IM; X |
Affiliation:
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Infectious Diseases Section, National Cancer Institute, Bethesda, MD 20892. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Bacterial Infections / complications Catheterization, Central Venous / adverse effects Child Child, Preschool Cohort Studies Female HIV Infections / complications* Humans Infant Male Opportunistic Infections / complications* Pseudomonas Infections / complications*, drug therapy Xanthomonas |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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