| Pseudomonas aeruginosa: acute lung injury or ventilator-associated pneumonia? | |
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MedLine Citation:
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PMID: 20935618 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative, aerobic, rod-shaped and polar-flagella bacterium with unipolar motility. Furthermore, it is an opportunistic pathogen responsible for ventilator-acquired pneumonia (VAP). VAP due to P. aeruginosa is usually multidrug-resistant and associated with severe infection and increased mortality. The goals of this review are as follows: (I) to present selected recent epidemiological literature characterizing the population at risk of P. aeruginosa pneumonia, (II) to describe some of the virulence factors of P. aeruginosa that are related to infection, and (III) to illustrate clinical outcomes of ventilated patients with large burdens of P. aeruginosa as well as the mechanism by which this bacterium may evade the host immune response. |
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Authors:
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L Berra; J Sampson; J Wiener-Kronish |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Minerva anestesiologica Volume: 76 ISSN: 1827-1596 ISO Abbreviation: Minerva Anestesiol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-11 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375272 Medline TA: Minerva Anestesiol Country: Italy |
Other Details:
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Languages: eng Pagination: 824-32 Citation Subset: IM |
Affiliation:
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Department of Anesthesia Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. lberra@partners.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cohort Studies Diagnosis, Differential Host-Pathogen Interactions Humans Multicenter Studies as Topic / statistics & numerical data Opportunistic Infections / diagnosis, epidemiology, microbiology Pneumonia, Bacterial / diagnosis*, epidemiology Pneumonia, Ventilator-Associated / diagnosis, epidemiology, etiology, microbiology* Postoperative Complications / diagnosis, epidemiology, microbiology Pseudomonas Infections / diagnosis*, epidemiology Pseudomonas aeruginosa / isolation & purification*, metabolism, pathogenicity, ultrastructure Thoracic Surgical Procedures Treatment Outcome Ventilator-Induced Lung Injury / diagnosis, epidemiology, microbiology* Virulence Wounds and Injuries / complications |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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