Document Detail


Pseudometastasis secondary to histoplasmosis infection: false-positive PET/CT findings.
MedLine Citation:
PMID:  19998468     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Positron emission computed tomography (PET)/CT is a common modality used in the workup of neoplastic conditions. However, false-positive results may be produced by underlying infectious processes. We report two cases of false-positive PET/CT studies secondary to histoplasmosis infections in both a pediatric and a young adult patient. After the diagnoses, one patient was observed with no therapy and the other received a complete course of itraconazole. In both cases biopsy results were positive for fungal elements consistent with histoplasmosis. Both patients were successfully managed and have had follow-up histoplasmosis titers that reveal resolving infections.
Authors:
Ross Perko; Yoav Messinger; Christopher Moertel
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric blood & cancer     Volume:  54     ISSN:  1545-5017     ISO Abbreviation:  Pediatr Blood Cancer     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-02-17     Completed Date:  2010-04-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101186624     Medline TA:  Pediatr Blood Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  621-3     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Antifungal Agents / therapeutic use
Bone Neoplasms / pathology
Diagnosis, Differential
False Positive Reactions
Female
Gastrointestinal Stromal Tumors / pathology
Histoplasmosis / drug therapy,  pathology*
Humans
Itraconazole / therapeutic use
Lung / microbiology,  pathology*
Male
Neoplasm Metastasis / pathology*
Positron-Emission Tomography*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
Tomography, X-Ray Computed*
Chemical
Reg. No./Substance:
0/Antifungal Agents; 84625-61-6/Itraconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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