| Pseudomembranous colitis associated with antibiotic prophylaxis in orthopaedic surgery. | |
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MedLine Citation:
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PMID: 3403605 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report 16 orthopaedic patients who had antibiotic-associated diarrhoea (pseudomembranous colitis) after operation. There was an association with the use of cephradine and with the prolongation of prophylaxis for more than three peri-operative doses. Five cases occurred as a cluster, suggesting that the causative agent, Clostridium difficile, may be infectious in some situations. |
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Authors:
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S R Cannon; P H Dyson; P J Sanderson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of bone and joint surgery. British volume Volume: 70 ISSN: 0301-620X ISO Abbreviation: J Bone Joint Surg Br Publication Date: 1988 Aug |
Date Detail:
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Created Date: 1988-09-21 Completed Date: 1988-09-21 Revised Date: 2010-11-10 |
Medline Journal Info:
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Nlm Unique ID: 0375355 Medline TA: J Bone Joint Surg Br Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 600-2 Citation Subset: AIM; IM |
Affiliation:
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Royal National Orthopaedic Hospital, Stanmore, Middlesex, England. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Cefuroxime / adverse effects, therapeutic use Cephalosporins / adverse effects* Cephradine / adverse effects*, therapeutic use Enterocolitis, Pseudomembranous / etiology* Female Humans Male Middle Aged Orthopedics* Postoperative Complications* Premedication / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Cephalosporins; 38821-53-3/Cephradine; 55268-75-2/Cefuroxime |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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