Document Detail

Pseudomelanosis of the duodenum. Endoscopic, histologic, and ultrastructural study of a case.
MedLine Citation:
PMID:  2458403     Owner:  NLM     Status:  MEDLINE    
We present the endoscopic, microscopic, and histochemical studies of a patient with pseudomelanosis of the duodenum. The pigment was located mainly in the lysosomes of macrophages in the lamina propria and was heterogeneous, showing features of melanin, pseudomelanin, and hemosiderin. The origin of this pigment remains unknown, but antihypertensive medication may have played a role.
G Castellano; F Canga; I Lopez; F Colina; J Gutierrez; R Costa; J A Solis-Herruzo
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of clinical gastroenterology     Volume:  10     ISSN:  0192-0790     ISO Abbreviation:  J. Clin. Gastroenterol.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-10-25     Completed Date:  1988-10-25     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7910017     Medline TA:  J Clin Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  150-4     Citation Subset:  IM    
Service of Gastroenterology, Hospital 1 de Octubre, Universidad Complutense, Madrid, Spain.
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MeSH Terms
Duodenal Diseases / pathology*
Duodenum / analysis*,  ultrastructure
Intestinal Mucosa / analysis
Lysosomes / analysis
Macrophages / analysis,  ultrastructure
Melanosis / pathology*
Microscopy, Electron
Pigments, Biological / analysis
Sex Factors
Staining and Labeling
Reg. No./Substance:
0/Pigments, Biological

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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