| Pseudo-random arterial modulation (PRAM): A novel arterial spin labeling approach to measure flow and blood transit times. | |
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MedLine Citation:
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PMID: 21990142 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: To investigate blood flow and transit time measurement, using the pseudo-random arterial modulation (PRAM). MATERIALS AND METHODS: PRAM is based on a pseudo-random sequence of inversions and noninversions of the arterial blood at a labeling plane inferior to the imaging plane. To accomplish this, a pseudo-continuous tagging is used to create inversion or noninversion prepulses before a gradient echo sequence and tested on phantoms and human volunteers. RESULTS: We have shown here that the PRAM technique can measure the velocity profile and the transit time accurately and efficiently both in a phantom and in vivo in a human brain. CONCLUSION: PRAM does not require separate control and label acquisition as is common in arterial spin labeling (ASL) but rather measures the distribution of transit times to a voxel within one integrated scan. The PRAM method is a model-free approach in measuring transit time distributions, and therefore ultimately should provide more accurate perfusion measurements. J. Magn. Reson. Imaging 2011;. © 2011 Wiley-Liss, Inc. |
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Authors:
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Mohammad-Reza Taei-Tehrani; Matthias J P Van Osch; Truman R Brown |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-11 |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: - ISSN: 1522-2586 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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Rutgers University Brain Imaging Center, Rutgers University, Newark, New Jersey, USA; Department of Radiology and Biomedical Engineering, Columbia University, New York, New York, USA. mr.tehrani@rutgers.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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