Document Detail

Pseudo-ischaemic ECG in a patient with amyotrophic lateral sclerosis surviving for a decade.
MedLine Citation:
PMID:  22665549     Owner:  NLM     Status:  MEDLINE    
A 58-year-old female with no history of heart disease was admitted to our hospital for abnormal ECG mimicking myocardial ischaemia. The ECG revealed persistent T-wave inversion in almost all leads, especially in precordial leads V2-V6. The patient had no complaints of chest pain, chest distress, short of breath or other atypical myocardial ischaemia symptoms. She had a history of amyotrophic lateral sclerosis (ALS) with a disease course more than 20 years. Examinations help rule out other diseases causing persistent T-wave inversion. Importantly, cardiac catheterisation showed nearly normal coronary arteries that could rule out myocardial ischaemia. Accordingly, the authors presumed that the pseudo-ischaemic ECG was associated with ALS in this patient. The findings of the present case provide new evidence that autonomic nervous system may involve in the pathophysiological progress of ALS.
Jian Zhang; Shi-Wei Yang; Zheng Wang; Guang-Ru Wei; Yu-Jie Zhou
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2012-02-25
Journal Detail:
Title:  BMJ case reports     Volume:  2012     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2012  
Date Detail:
Created Date:  2012-06-05     Completed Date:  2013-02-01     Revised Date:  2014-03-12    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
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MeSH Terms
Amyotrophic Lateral Sclerosis / physiopathology*
Cardiac Catheterization
Heart / physiopathology
Middle Aged
Myocardial Ischemia / physiopathology*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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