Document Detail

"Pseudo-giant P-waves" and pericardial friction rub following chlorpromazine therapy.
MedLine Citation:
PMID:  1015518     Owner:  NLM     Status:  MEDLINE    
A patient is presented who manifested two previously undescribed complications of chlorpromazine therapy: a transient pericardial friction rub and "pseudo-giant P waves". After slowing of the heart rate, the "giant P-waves" proved to be superimposed U and P-waves. His history demonstrates the protean and at times unusual complications of chlorpromazine therapy and illustrates the dramatic therapeutic effects diphenhydramine may have in reversing some of this toxicity.
J Bausher; H S Goldstein; M D Aronson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  272     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:    1976 Nov-Dec
Date Detail:
Created Date:  1977-03-15     Completed Date:  1977-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  357-9     Citation Subset:  AIM; IM    
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MeSH Terms
Chlorpromazine / adverse effects*
Heart Auscultation*
Heart Rate / drug effects*
Heart Sounds*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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