Document Detail


PSEUDALLESCHERIA ENDOPHTHALMITIS: FOUR CASES OVER 15 YEARS IN QUEENSLAND, AUSTRALIA, AND A REVIEW OF THE LITERATURE.
MedLine Citation:
PMID:  24695065     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE:: To describe the clinical features and outcomes of patients with culture-proven Pseudallescheria endophthalmitis in the context of previously published cases.
METHODS:: A multicenter, retrospective, consecutive case series was undertaken. Pathology records were reviewed for all patients with Pseudallescheria endophthalmitis on vitreous/aqueous cultures from June 1998 to June 2013 throughout Queensland, Australia.
RESULTS:: Three females and 1 male aged 60 to 78 years were identified. All patients had endogenous endophthalmitis, had an underlying malignancy, and were from South East Queensland. Vitreous cultures identified Scedosporium auranticum in two cases and Scedosporium prolificans and Scedosporium apiospermum in one case each. All isolates were sensitive to voriconazole. Enucleation was required in two patients. Two patients had final best-corrected visual acuities of perception of light and no perception of light, respectively.
CONCLUSION:: Endophthalmitis caused by species of the P. boydii complex is a devastating condition with poor visual outcomes. It is a condition that is difficult to treat because of its variable antifungal agent resistance.
Authors:
Thomas P Moloney; Joseph Park
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-4-1
Journal Detail:
Title:  Retina (Philadelphia, Pa.)     Volume:  -     ISSN:  1539-2864     ISO Abbreviation:  Retina (Philadelphia, Pa.)     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-4-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309919     Medline TA:  Retina     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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