Document Detail

Proximal protection in recanalization of totally occluded saphenous vein grafts in acute coronary syndrome.
MedLine Citation:
PMID:  20146345     Owner:  NLM     Status:  MEDLINE    
Percutaneous treatment of old, degenerated saphenous vein grafts (SVG) is associated with a high likelihood of major adverse cardiac events. When an acute coronary syndrome (ACS) develops in a patient with old SVG, fresh thrombus may superimpose on an old, degenerative atheroma: a sudden increase in the athero-thrombotic burden ensues with consequent, frequent total occlusion of the lumen. In this scenario, transluminal recanalization of the graft is usually associated with the highest chance of distal embolization and no-reflow and positioning of an embolic protection device (EPD) is almost mandatory. However, distal EPD are difficult to place when the vessel is totally occluded and do not completely avoid distal embolization. We report two cases of totally occluded SVG in patients admitted for ACS that were recanalized with the aid of a proximal EPD system with angiographic and clinical success.
Paolo Sganzerla; Emanuela Tavasci
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  75     ISSN:  1522-726X     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-02     Completed Date:  2010-09-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1051-5     Citation Subset:  IM    
Division of Cardiology, Humanitas Gavazzeni, Bergamo, Italy.
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MeSH Terms
Acute Coronary Syndrome / etiology,  physiopathology,  radiography,  therapy*
Angioplasty, Transluminal, Percutaneous Coronary* / adverse effects,  instrumentation
Cardiovascular Agents / administration & dosage
Coronary Angiography
Coronary Artery Bypass / adverse effects*
Drug-Eluting Stents
Embolism / etiology,  prevention & control
Equipment Design
Filtration / instrumentation
Graft Occlusion, Vascular / etiology,  physiopathology,  radiography,  therapy*
Middle Aged
Prosthesis Design
Saphenous Vein / physiopathology,  radiography,  transplantation*
Sirolimus / administration & dosage,  analogs & derivatives
Thrombosis / etiology,  physiopathology,  radiography,  therapy*
Treatment Outcome
Vascular Patency
Reg. No./Substance:
0/Cardiovascular Agents; 0/Metals; 159351-69-6/everolimus; 53123-88-9/Sirolimus

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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