Document Detail

Proximal tibial bone density is preserved after unicompartmental knee arthroplasty.
MedLine Citation:
PMID:  23325112     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Bone mineral density (BMD) in the proximal tibia decreases after TKA and is believed to be a factor in implant migration and loosening. Unicompartmental knee arthroplasty (UKA) is a less invasive procedure preserving knee compartments unaffected by degeneration. Finite element studies have suggested UKA may preserve BMD and that implants of differing stiffnesses might differentially affect BMD but these notions have not been clinically confirmed.
QUESTIONS/PURPOSES: We therefore asked whether (1) proximal tibial BMD decreases after UKA, and (2) a cemented metal tibial component with a mobile polyethylene (PE) bearing would have greater BMD loss than a cemented PE tibial component.
METHODS: We prospectively followed 48 patients who underwent 50 UKAs using one of two implants: one with a cemented metal tibial baseplate and a mobile PE insert (n = 26) and one with a cemented all-PE tibial component (n = 24). In followup we assessed pain and function (Oxford Knee Score, SF-12, The Knee Society Score(©)) and radiographs. BMD changes were assessed using quantitative CT osteodensitometry performed postoperatively and at 1 and 2 years after the index procedure.
RESULTS: Mean cancellous BMD decreased 1.9% on the medial side and 1.1% on the lateral side. Mean cortical BMD was static, decreasing 0.4% on the medial side and increasing 0.5% on the lateral side. The greatest observed difference between implants for any region was 3.7%. There were no differences in pain or functional outcome scores.
CONCLUSIONS: BMD was preserved 2 years after UKA with no major differences seen between implant types.
Bradley I Richmond; Simon V Hadlow; Tim G Lynskey; Cameron G Walker; Jacob T Munro
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2013-01-17
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  471     ISSN:  1528-1132     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-02     Completed Date:  2013-05-22     Revised Date:  2014-05-07    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1661-9     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Arthralgia / etiology
Arthroplasty, Replacement, Knee* / adverse effects,  instrumentation
Biomechanical Phenomena
Bone Cements / therapeutic use
Bone Density*
Knee Joint / physiopathology,  radiography,  surgery*
Knee Prosthesis
Middle Aged
Pain Measurement
Pain, Postoperative / etiology
Prospective Studies
Prosthesis Design
Recovery of Function
Tibia / physiopathology,  radiography,  surgery*
Time Factors
Tomography, X-Ray Computed
Treatment Outcome
Reg. No./Substance:
0/Bone Cements; 9002-88-4/Polyethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Synthesis of graphene-conjugated polymer nanocomposites for electronic device applications.
Next Document:  Evaluation of the effects of nicorandil and its molecular precursor (without radical NO) on prolifer...