Document Detail

Provocation of silence.
MedLine Citation:
PMID:  19181867     Owner:  NLM     Status:  MEDLINE    
We describe the development of a Brugada ECG together with sinus- and ventricular arrest after intravenous flecainide for atrial fibrillation in a patient in whom eventually a SCN5a mutation was identified. Unrecognized SCN5A mutations could underlie class IC-induced sinus arrest and conduction defects in some patients.
Jurren M van Opstal; Paul G A Volders; Harry J G M Crijns
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-30
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  11     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-02-25     Completed Date:  2009-05-28     Revised Date:  2011-07-22    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  385-7     Citation Subset:  IM    
Department of Cardiology, Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6202 AZ Maastricht, The Netherlands.
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MeSH Terms
Atrial Fibrillation / diagnosis*,  genetics*
Brugada Syndrome / diagnosis*,  genetics*
Genetic Predisposition to Disease / genetics
Middle Aged
Muscle Proteins / genetics*
Sodium Channels / genetics*
Reg. No./Substance:
0/Muscle Proteins; 0/Sodium Channels; 0/sodium channel protein type 5 subunit alpha

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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