Document Detail


Provisional TAP-stenting strategy to treat bifurcated lesions with drug-eluting stents: one-year clinical results of a prospective registry.
MedLine Citation:
PMID:  19805841     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess the clinical outcome of unselected patients undergoing drug-eluting stent (DES) implantation on bifurcated lesions using a "provisional T And small Protrusion (TAP)" stenting strategy. METHODS: Consecutive patients undergoing DES implantation on one major bifurcation lesion were treated by main-vessel (MV) stenting, followed (if needed) by side-branch (SB) rewiring (with a "pullback" technique) and kissing balloon. SB stenting was performed according to the TAP-technique in selected cases. The endpoint of the study was a 12-month incidence of major adverse cardiac events (MACE) defined as cardiac death, myocardial infarction (MI), stent thrombosis and target vessel revascularization (TVR). RESULTS: The study population included 266 patients (9% unprotected left main). Only 19 patients (7.1%) (with more complex angiographic features) received stents in both the MV and SB using the TAP-technique. Overall, 22 (8.2%) patients had MACE at 1 year. Observed, non-hierarchical MACE were: 1 (0.4%) cardiac death, 11 (4.1%) MI, 2 probable stent thromboses and 12 (4.5%) TVRs. Postprocedural troponin T increase and adverse events up to 12 months were similar between patients treated by MV stenting only or double stenting. CONCLUSIONS: In unselected patients undergoing DES implantation on bifurcated lesions, a provisional TAP-stenting strategy (with a low rate of SB stenting) appears to be safe and effective.
Authors:
Francesco Burzotta; Gregory Angelo Sgueglia; Carlo Trani; Giovanni Paolo Talarico; Santiago Federico Coroleu; Simona Giubilato; Giampaolo Niccoli; Maura Giammarinaro; Italo Porto; Antonio Maria Leone; Rocco Mongiardo; Mario Attilio Mazzari; Giovanni Schiavoni; Filippo Crea
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  21     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-06     Completed Date:  2010-02-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  532-7     Citation Subset:  IM    
Affiliation:
Institute of Cardiology, Catholic University of the Sacred Heart, Via Prati Fiscali 158, 00141 Rome, Italy. f.burzotta@rm.unicatt.it
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MeSH Terms
Descriptor/Qualifier:
Aged
Angioplasty, Transluminal, Percutaneous Coronary / instrumentation*,  methods*
Coronary Artery Disease / classification*,  therapy*
Drug-Eluting Stents* / adverse effects
Female
Follow-Up Studies
Humans
Incidence
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction / epidemiology
Prospective Studies
Registries
Retrospective Studies
Thrombosis / epidemiology
Treatment Outcome
Comments/Corrections
Comment In:
J Invasive Cardiol. 2009 Oct;21(10):538   [PMID:  19805842 ]

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