| Provision of laboratory services for lipid analysis in the United Kingdom. | |
| | |
MedLine Citation:
|
PMID: 17456295 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: National guidelines have been developed in the UK to reduce coronary heart disease mortality. This audit assesses provision of lipid analyses by UK Clinical Biochemistry services to support their implementation. METHODS: Audit standards were derived from published guidelines. A questionnaire based on these was circulated to all UK Clinical Biochemistry laboratories. RESULTS: Of 108 replies, routine lipid profiles included triglycerides, HDL-, LDL-cholesterol and total:HDL cholesterol ratio in 98, 85, 72 and 44%, respectively. Only 33% and 27% analysed triglycerides and HDL, respectively, when asked simply to measure cholesterol. Seventy-six percent of the reports stated whether specimens were collected after fasting. For primary prevention, 46% of laboratories stated results should be interpreted in association with other risk factors; 20% referred explicitly to national/local guidelines. Only 19 laboratories quoted secondary prevention treatment thresholds for total cholesterol or LDL-cholesterol. Sixty laboratories occasionally added extra tests and/or interpretive comments. Eight laboratories appeared to provide no input from senior medical/scientific staff into report validation. CONCLUSIONS: These results indicate scope for improvement in the provision of lipid analyses and of information to support their interpretation. We recommend laboratories should routinely provide LDL- and non-HDL-cholesterol results, and that reports should quote treatment thresholds/targets in keeping with current guidelines. |
| | |
Authors:
|
A C J Hutchesson; M J O'Kane; R D Neely; D A Oleesky |
Related Documents
:
|
20032565 - Lipid profiles in the untreated patients with hashimoto thyroiditis and the effects of ... 20683785 - Revisiting dietary cholesterol recommendations: does the evidence support a limit of 30... 19932775 - Effects of combination lipid therapy on coronary stenosis progression and clinical card... 7039445 - Colestipol and probucol: treatment of primary and familial hypercholesterolemia and ame... 15844705 - Systemic iron supplementation replenishes iron stores without enhancing colon carcinoge... 17674125 - Influence of different co-substrates biochemical composition on raw sludge co-composting. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Annals of clinical biochemistry Volume: 44 ISSN: 0004-5632 ISO Abbreviation: Ann. Clin. Biochem. Publication Date: 2007 May |
Date Detail:
|
Created Date: 2007-04-25 Completed Date: 2007-06-14 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0324055 Medline TA: Ann Clin Biochem Country: England |
Other Details:
|
Languages: eng Pagination: 273-80 Citation Subset: IM |
Affiliation:
|
Department of Clinical Chemistry, Royal Bolton Hospital, Bolton, UK. Andrew.Hutchesson@rbh.nhs.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Great Britain Guidelines as Topic Humans Laboratories / organization & administration* Lipids / blood*, classification Questionnaires |
| Chemical | |
Reg. No./Substance:
|
0/Lipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Osteopontin and C-reactive protein in Egyptian patients affected with tuberculous and malignant pleu...
Next Document: Salivary cortisol reflects serum cortisol: analysis of circadian profiles.