| Proven intra and interobserver reliability in the echographic assessments of body fat changes related to HIV associated Adipose Redistribution Syndrome (HARS). | |
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MedLine Citation:
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PMID: 18691025 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To prove intra- and inter-observer's reliability of ultrasound (US) in the assessment of lipoatrophic findings related to the HIV associated Adipose Redistribution Syndrome (HARS). PATIENTS AND METHODS: In two separated sessions, 2 consecutive measurements of subcutaneous fat thickness (SFT) were performed by each observer at the deepest point of Bichat pad, the dorsal face of arm and the mid thigh for the assessment of facial, brachial and crural lipoatrophy, respectively. We enrolled 20 HIV patients, rotating an experienced and untrained sonologist. The assessments were performed avoiding any stand off pads in the skin and excluding artefacts due to the too abundant quantity of gel to obtaining, with minimal transducer pressure, the best resolution of the reference points. RESULTS: Means of facial, brachial and crural SFT showed no significant differences between the workers. Coefficients of variability (SD/mean x100) were similar for facial (ranges: 4.7-5.2% vs 4.9-5.6%, respectively), brachial (ranges: 5.8-8.4% vs 9.7-11.2%) and crural SFTs (ranges: 5.9-6% vs 6.2-8.7%). There was greater consistency in the measurements performed by the experienced vs the untrained worker. Inter-observer agreement, assessed through kappa statistic (k) analysis, confirmed increased measurement's agreement in the facial (k ranged from 0.40 to 0.60), brachial (k: 0.23-0.63) and crural SFT assessments (k: 0.58-0.70) from the 1(st) to 2(nd) session. CONCLUSIONS: US shows low intra observer variability and good inter observer reliability in the assessment of body fat changes related to the HARS. The different degree of consistency by the workers and the improvement of interobserver agreement, suggest to stating a well defined period of training to obtain better US reliability. |
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Authors:
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Rosario Gulizia; Alessia Uglietti; Antonella Grisolia; Cristina Gervasoni; Massimo Galli; Carlo Filice |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Current HIV research Volume: 6 ISSN: 1873-4251 ISO Abbreviation: Curr. HIV Res. Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-08-11 Completed Date: 2009-01-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101156990 Medline TA: Curr HIV Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 276-8 Citation Subset: IM |
Affiliation:
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Division of Infectious and Tropical Diseases, Foundation IRCCS S Matteo, University of Pavia, Italy. rosario.gulizia@libero.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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ultrasonography Arm Body Composition* Face HIV Infections / complications* HIV-Associated Lipodystrophy Syndrome / ultrasonography* Humans Observer Variation Subcutaneous Fat / ultrasonography* Subcutaneous Fat, Abdominal / ultrasonography Thigh |
| Comments/Corrections | |
Comment On:
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Curr HIV Res. 2007 Sep;5(5):459-66
[PMID:
17896965
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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