Document Detail

Protothecosis complicating prolonged endotracheal intubation: case report and literature review.
MedLine Citation:
PMID:  1457668     Owner:  NLM     Status:  MEDLINE    
Prototheca species are ubiquitous, aerobic, unicellular algae closely related to the green algae Chlorella. Their involvement in human disease--in both immunocompetent and immunocompromised patients--has been reported with increasing frequency. The wide array of presentations has included cutaneous, subcutaneous, mucosal, bursal, catheter-related, and (in rare instances) systemic disease. We report a case of protothecosis complicating prolonged endotracheal intubation presenting as a nasopharyngeal ulceration with a soft-tissue mass, and we review the presentation, treatment, and outcome of the 59 previously reported cases of protothecosis. Optimal therapy for protothecosis includes excision (where possible) followed by systemic administration of amphotericin B; the sole exception is in the case of olecranon bursitis, where excision alone appears curative. The role of the newer imidazoles is yet to be determined.
V R Iacoviello; P C DeGirolami; J Lucarini; K Sutker; M E Williams; C A Wanke
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  15     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-01-12     Completed Date:  1993-01-12     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  959-67     Citation Subset:  IM    
Division of Infectious Diseases, New England Deaconess Hospital, Harvard Medical School, Boston, Massachusetts 02215.
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MeSH Terms
Infection / microbiology
Intubation, Intratracheal / adverse effects*
Nasopharyngeal Diseases / etiology,  microbiology*

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