| Proton MR spectroscopy of the brain in patients treated with TIPS. | |
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MedLine Citation:
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PMID: 11092477 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the utility of proton MR spectroscopy (MRS) for the early detection of hepatic encephalopathy (HE) after transjugular intrahepatic portosystemic shunting (TIPS). MATERIAL AND METHODS: Six patients, who underwent TIPS for treatment of portal hypertension, were examined by MRS I week before and 1 week after TIPS. They were simultaneously clinically examined for number connection test, blood NH3 level, liver function test and the Fischer ratio. RESULT: Three of 6 patients showed overt HE 1 to 5 weeks after TIPS and the other 3 patients did not show overt HE. The overt HE group showed the larger ratio of the amounts of glutamine and glutamate/myo-inositol (Glx/MI) than that of non-overt HE group (p<0.05). CONCLUSION: The Glx/MI ratio estimated by MRS was useful for early detection of HE after TIPS. |
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Authors:
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M Hamuro; K Nakamura; T Matsuoka; T Kaminou; M Higashida; R Yamada |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 41 ISSN: 0284-1851 ISO Abbreviation: Acta Radiol Publication Date: 2000 Nov |
Date Detail:
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Created Date: 2000-11-27 Completed Date: 2000-12-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 567-71 Citation Subset: IM |
Affiliation:
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Department of Radiology, Osaka City University Medical School, Osaka, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Brain Chemistry* Female Glutamic Acid / analysis Glutamine / analysis Hepatic Encephalopathy / diagnosis*, etiology Humans Hypertension, Portal / surgery Inositol / analysis Liver Function Tests Magnetic Resonance Spectroscopy* Male Middle Aged Portasystemic Shunt, Transjugular Intrahepatic / adverse effects* |
| Chemical | |
Reg. No./Substance:
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56-85-9/Glutamine; 56-86-0/Glutamic Acid; 6917-35-7/Inositol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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