Document Detail


Proteus syndrome: ocular complications.
MedLine Citation:
PMID:  3282059     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Proteus syndrome is a recently recognized hamartoneoplastic malformation syndrome of uncertain etiology and variable expression, whose cardinal manifestations are pigmented nevi, hemihypertrophy, macrodactly, lipomata, and cerebroid-gyriform configuration of the skin on the soles of the feet. The characteristic features may be present at birth but become more apparent with time. In the past this syndrome has been confused with other overgrowth disorders such as neurofibromatosis, Klippel-Trenaunay-Weber syndrome, Maffucci syndrome, and Bannayan syndrome. The ophthalmic features of the proteus syndrome require clarification. We review the ocular findings in 16 previously described cases and describe the findings unique to our patient, in particular, unilateral epibulbar and suspected posterior segment hamartomas.
Authors:
J P Burke; R Bowell; N O'Doherty
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of pediatric ophthalmology and strabismus     Volume:  25     ISSN:  0191-3913     ISO Abbreviation:  J Pediatr Ophthalmol Strabismus     Publication Date:    1988 Mar-Apr
Date Detail:
Created Date:  1988-05-26     Completed Date:  1988-05-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7901143     Medline TA:  J Pediatr Ophthalmol Strabismus     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  99-102     Citation Subset:  IM    
Affiliation:
Department of Paediatric Ophthalmology, Children's Hospital, Dublin, Ireland.
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MeSH Terms
Descriptor/Qualifier:
Child
Eye Diseases / complications*
Female
Foot Deformities, Congenital / complications
Gigantism / complications*
Hamartoma / complications*
Hand Deformities, Congenital / complications
Humans
Nystagmus, Pathologic / complications*,  physiopathology
Orbital Neoplasms / complications*
Skin Diseases / complications*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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