| Proteomic responses of skeletal and cardiac muscle to exercise. | |
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MedLine Citation:
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PMID: 21679117 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Regular exercise is effective in the prevention of chronic diseases and confers a lower risk of death in individuals displaying risk factors such as hypertension and dyslipidemia. Thus, knowledge of the molecular responses to exercise provides a valuable contrast for interpreting investigations of disease and can highlight novel therapeutic targets. While exercise is an everyday experience and can be conceptualized in simple terms, it is also a complex physiological phenomenon and investigation of exercise responses requires sophisticated analytical techniques and careful standardization of the exercise stimulus. Proteomic investigation of exercise is in its infancy but the ability to link changes in function with comprehensive changes in protein expression and post-translational modification holds great promise for advancing physiology. This article highlights recent pioneering work investigating the effects of exercise in skeletal and cardiac muscle that has uncovered novel mechanisms underlying the benefits of physical activity. |
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Authors:
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Jatin G Burniston; Eric P Hoffman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Expert review of proteomics Volume: 8 ISSN: 1744-8387 ISO Abbreviation: Expert Rev Proteomics Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-06-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101223548 Medline TA: Expert Rev Proteomics Country: England |
Other Details:
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Languages: eng Pagination: 361-77 Citation Subset: IM |
Affiliation:
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Muscle Physiology and Proteomics Laboratory, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, L3 3AF, UK. j.burniston@ljmu.ac.uk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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