Document Detail

Proteome dynamics during contractile and metabolic differentiation of bovine foetal muscle.
MedLine Citation:
PMID:  22444818     Owner:  NLM     Status:  In-Data-Review    
Contractile and metabolic properties of bovine muscles play an important role in meat sensorial quality, particularly tenderness. Earlier studies based on Myosin heavy chain isoforms analyses and measurements of glycolytic and oxidative enzyme activities have demonstrated that the third trimester of foetal life in bovine is characterized by contractile and metabolic differentiation. In order to complete this data and to obtain a precise view of this phase and its regulation, we performed a proteomic analysis of Semitendinosus muscle from Charolais foetuses analysed at three stages of the third trimester of gestation (180, 210 and 260 days). The results complete the knowledge of important changes in the profiles of proteins from metabolic and contractile pathways. They provide new insights about proteins such as Aldehyde dehydrogenase family, Enolase, Dihydrolipoyl dehydrogenase, Troponin T or Myosin light chains isoforms. These data have agronomical applications not only for the management of beef sensorial quality but also in medical context, as bovine myogenesis appears very similar to human one.
T Chaze; B Meunier; C Chambon; C Jurie; B Picard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Animal : an international journal of animal bioscience     Volume:  3     ISSN:  1751-7311     ISO Abbreviation:  Animal     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2012-03-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101303270     Medline TA:  Animal     Country:  England    
Other Details:
Languages:  eng     Pagination:  980-1000     Citation Subset:  -    
1INRA, UR1213, Unité de Recherches sur les Herbivores, Equipe Croissance et Métabolisme du Muscle, F-63122 Saint-Genès Champanelle, France.
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