Document Detail


Proteinuria in intact and splenectomized dogs after running and swimming.
MedLine Citation:
PMID:  6511148     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The occurrence of post-exercise proteinuria was investigated in intact and splenectomized dogs after treadmill running and swimming and compared to control experiments. Albumin and lysozyme were measured by radial diffusion. Urinary protein was analyzed by SDS-polyacrylamide gel electrophoresis. Swimming in the splenectomized dogs increased the albumin excretion in the first 30 min after exercise from 0.03 to 0.22 mg X min-1 and the lysozyme excretion in the same period from 0.11 to 0.75 micrograms X min-1. Swimming in intact dogs caused smaller increase in the lysozyme and albumin excretions during the exercise period itself as well as in the albumin excretion in the first 30 min after exercise. Running had no effect on urinary albumin or lysozyme but increased the low molecular weight protein fraction in the splenectomized dogs. Plasma lactate concentrations were higher during swimming in the splenectomized dogs than in the intact dogs. Possible mechanisms of post-exercise proteinuria are discussed.
Authors:
J A Joles; M Sanders; J Velthuizen; J M Den Hertog; C Van Dijk
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of sports medicine     Volume:  5     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-02-14     Completed Date:  1985-02-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  311-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs
Female
Kidney Glomerulus / physiopathology
Kidney Tubules / physiopathology
Male
Muramidase / urine
Osmolar Concentration
Potassium / urine
Proteinuria / etiology*
Random Allocation
Running*
Sodium / urine
Splenectomy*
Swimming*
Chemical
Reg. No./Substance:
7440-09-7/Potassium; 7440-23-5/Sodium; EC 3.2.1.17/Muramidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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