Document Detail


Proteins involved in binding and cellular uptake of nucleic acids.
MedLine Citation:
PMID:  16827649     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The study of mechanisms of nucleic acid transport across the cell membrane is valuable both for understanding the biological function of extracellular nucleic acids and the practical use of nucleic acids in gene therapy. It has been clearly demonstrated that cell surface proteins are necessary for transport of nucleic acids into cells. A large amount of data has now been accumulated about the proteins that participate in nucleic acid transport. The methods for revealing and identification of these proteins, possible mechanisms of protein-mediated transport of nucleic acids, and cellular functions of these proteins are described.
Authors:
B P Chelobanov; P P Laktionov; V V Vlasov
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Biochemistry. Biokhimii͡a     Volume:  71     ISSN:  0006-2979     ISO Abbreviation:  Biochemistry Mosc.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-07-10     Completed Date:  2006-09-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376536     Medline TA:  Biochemistry (Mosc)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  583-96     Citation Subset:  IM    
Affiliation:
Institute of Biochemistry, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, 630117, Russia. chelobanov@soramn.ru
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Transport, Active
DNA-Binding Proteins / physiology*
Humans
Nucleic Acids / metabolism*
RNA Transport*
Chemical
Reg. No./Substance:
0/DNA-Binding Proteins; 0/Nucleic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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