| Protein-losing gastroenteropathy and retinitis associated with cytomegalovirus infection in an immunocompetent infant: a case report. | |
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MedLine Citation:
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PMID: 14658065 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 6-week-old immunocompetent girl developed protein-losing gastroenteropathy (PLGE) and retinitis associated with cytomegalovirus (CMV) infection. At presentation, CMV antigenaemia (6 cells/46,000 white blood cells) and its DNA were detected in the patient's blood and in the mother's milk. Intravenous ganciclovir and gamma-globulin rapidly ameliorated all symptoms and CMV antigenaemia disappeared. No immunological defects were identified in this patient. To the best of our knowledge, this case involves the youngest known immunocompetent patient demonstrating CMV-induced PLGE and retinitis. CONCLUSION: breast-feeding by a cytomegalovirus-positive mother can be a primary cause of early onset cytomegalovirus infection in infants. |
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Authors:
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Manabu Iwanaga; Masafumi Zaitsu; Eiichi Ishii; Yoichi Nishimura; Shigeyasu Inada; Hiroka Yoshiki; Satoshi Okinami; Yuhei Hamasaki |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2003-12-05 |
Journal Detail:
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Title: European journal of pediatrics Volume: 163 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-01-29 Completed Date: 2004-05-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: Germany |
Other Details:
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Languages: eng Pagination: 81-4 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, 849-8501 Saga, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antiviral Agents / therapeutic use* Breast Feeding / adverse effects* Cytomegalovirus Infections / complications*, drug therapy, etiology Ganciclovir / therapeutic use* Humans Infant Milk, Human / virology Protein-Losing Enteropathies / complications* Retinitis / complications* |
| Chemical | |
Reg. No./Substance:
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0/Antiviral Agents; 82410-32-0/Ganciclovir |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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