Document Detail

Protein-losing enteropathy associated with egg allergy in a 5-month-old boy.
MedLine Citation:
PMID:  18361105     Owner:  NLM     Status:  MEDLINE    
Protein-losing enteropathy (PLE), the manifestation of a diverse set of disorders, is characterized by excessive loss of plasma proteins into the affected portions of the gastrointestinal tract, and this results in hypoalbuminemia. A 5-month-old breastfed boy presented severe PLE with hypogammaglobulinemia, hypocalcemia, and hypomagnesemia induced by an egg allergy. He developed hypocalcemic convulsions. The diagnosis of PLE was confirmed by elevated fecal alpha1-antitrypsin clearance and a positive finding on a protein-losing scintigram. His allergy to egg delivered through maternal milk was confirmed as the cause of PLE, since the mother's elimination of egg from her diet improved his condition and maternal egg challenge provoked symptoms of diarrhea, vomiting, and elevated alpha1-antitrypsin clearance. At the time of writing, he is 22 months old and has experienced no further episodes after the elimination of egg-containing food.
M Kondo; T Fukao; K Omoya; N Kawamoto; M Aoki; T Teramoto; H Kaneko; N Kondo
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of investigational allergology & clinical immunology     Volume:  18     ISSN:  1018-9068     ISO Abbreviation:  J Investig Allergol Clin Immunol     Publication Date:  2008  
Date Detail:
Created Date:  2008-03-25     Completed Date:  2008-05-06     Revised Date:  2013-07-31    
Medline Journal Info:
Nlm Unique ID:  9107858     Medline TA:  J Investig Allergol Clin Immunol     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  63-6     Citation Subset:  IM    
Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.
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MeSH Terms
Breast Feeding
Egg Hypersensitivity / complications*
Immunoglobulin E / blood
Protein-Losing Enteropathies / etiology*
Reg. No./Substance:
37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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