Document Detail

Protein localization by recognition of membrane curvature.
MedLine Citation:
PMID:  20951078     Owner:  NLM     Status:  MEDLINE    
Bacteria often sort proteins to specific subcellular locations, but many of the chemical beacons that specify those sites and subsequently recruit proteins have not been identified. Recent reports suggest that some bacterial proteins localize to specific subcellular sites by recognizing either convex or concave membrane curvature. Thus, degrees of membrane curvature, dictated by the shape of the cell, can define a geometric cue for the recruitment of curvature-sensing proteins.
Kumaran S Ramamurthi
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural; Review     Date:  2010-10-13
Journal Detail:
Title:  Current opinion in microbiology     Volume:  13     ISSN:  1879-0364     ISO Abbreviation:  Curr. Opin. Microbiol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-30     Completed Date:  2011-03-01     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  9815056     Medline TA:  Curr Opin Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  753-7     Citation Subset:  IM    
Copyright Information:
Published by Elsevier Ltd.
Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.
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MeSH Terms
Bacteria / metabolism*
Bacterial Proteins / metabolism*
Cell Membrane / metabolism*,  ultrastructure
Membrane Proteins / metabolism*
Models, Biological
Protein Transport
Grant Support
Reg. No./Substance:
0/Bacterial Proteins; 0/Membrane Proteins

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