Document Detail


Protein-calorie malnutrition in liver cirrhosis.
MedLine Citation:
PMID:  1392415     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this article is to present detailed data on the nutritional assessment in cirrhotic patients. The exact frequency and types of malnutrition, its associations with the aetiology of liver disease, liver dysfunction and clinical staging in liver cirrhosis are unknown. A new classification system is presented which may help to suggest some interventional guidelines. Physical (anthropometry, 24-h urinary creatinine excretion, bioelectrical impedance analysis (BIA), total body potassium counting, ultrasound examination) and metabolic (indirect calorimetry) assessment of nutritional status was therefore performed in 123 patients with liver cirrhosis, who were considered as potential candidates for liver transplantation. Data were related to the clinical, biochemical, histological and prognostic data of liver disease. Of our patients 65% showed some signs of protein-calorie malnutrition as indicated by low body cell mass, reduced serum albumin concentrations or abnormal skinfold thickness. Of these 34% were considered as "kwashiorkor-like" (normal body composition, serum albumin less than 35 g/l), and 18% were "marastic" (reduced body weight, body cell mass, and fat mass). However, 49% of the malnourished group had reduced body cell mass in association with increased fat mass and frequently presented with a normal body weight ("mixed" or "obese" type). Protein-calorie malnutrition did not correlate with the aetiology of the disease and biochemical parameters of liver function. Malnutrition was observed at all clinical stages but was more frequently seen at advanced stages. We conclude that malnutrition associated with liver cirrhosis is not a clear phenomenon. Its clinical presentation is heterogenous and not reflected by the histological or biochemical parameters of liver disease.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
H U Lautz; O Selberg; J Körber; M Bürger; M J Müller
Related Documents :
10023735 - A comparison of dual-energy x-ray absorptiometry and somatometrics for determining body...
1600705 - Body fat and overweight among children and adolescents with diabetes mellitus.
19585755 - Correlation of pulmonary function tests with body fat percentage in young individuals.
2735455 - Adipose tissue dynamics during cyclic weight loss and weight gain of ground squirrels.
17582105 - Prepartum behavior and dry matter intake identify dairy cows at risk for metritis.
25404025 - Dietary polyunsaturated fatty acids increase survival and decrease bacterial load durin...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Clinical investigator     Volume:  70     ISSN:  0941-0198     ISO Abbreviation:  Clin Investig     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-11-02     Completed Date:  1992-11-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9207154     Medline TA:  Clin Investig     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  478-86     Citation Subset:  IM    
Affiliation:
Abteilung Gastroenterologie und Hepatologie, Medizinische Hochschule Hannover.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Anthropometry
Energy Metabolism
Female
Humans
Liver Cirrhosis / complications*,  etiology,  physiopathology
Liver Function Tests
Male
Middle Aged
Nutrition Assessment
Prognosis
Protein-Energy Malnutrition / etiology*,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prevention and treatment of ulcers induced by nonsteroidal anti-inflammatory drugs.
Next Document:  Effect of ethanol and commonly ingested alcoholic beverages on gastric emptying and gastrointestinal...