Document Detail


Protein-based biorefining: metabolic engineering for production of chemicals and fuel with regeneration of nitrogen fertilizers.
MedLine Citation:
PMID:  23296497     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Threats to stable oil supplies and concerns over environmental emissions have pushed for renewable biofuel developments to minimize dependence on fossil resources. Recent biofuel progress has moved towards fossil resource-independent carbon cycles, but environmental issues regarding use of nitrogen fertilizers have not been addressed on a global scale. The recently demonstrated conversion of waste protein biomass into advanced biofuels and renewable chemicals, while recycling nitrogen fertilizers, offers a glimpse of the efforts needed to balance the nitrogen cycle at scale. In general, the catabolism of protein into biofuels is challenging because of physiological regulation and thermodynamic limitations. This conversion became possible with metabolic engineering around ammonia assimilation, intracellular nitrogen flux, and quorum sensing. This review highlights the metabolic engineering solutions in transforming those cellular processes into driving forces for the high yield of chemical products from protein.
Authors:
David G Wernick; James C Liao
Related Documents :
10343077 - Reduced blood bcl-2 protein concentration in patients on hemodialysis.
11527397 - 14-3-3 protein-activated and autoinhibited forms of plasma membrane h(+)-atpase.
16487927 - Monad, a wd40 repeat protein, promotes apoptosis induced by tnf-alpha.
15664187 - Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a...
20728537 - An insight into the sialome of blood-feeding nematocera.
20478917 - Cellular modelling: experiments and simulation to develop a physiological model of g-pr...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-8
Journal Detail:
Title:  Applied microbiology and biotechnology     Volume:  -     ISSN:  1432-0614     ISO Abbreviation:  Appl. Microbiol. Biotechnol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406612     Medline TA:  Appl Microbiol Biotechnol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, 5531 Boelter Hall, 420 Westwood Plaza, Los Angeles, CA, 90095, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  PdSNF1, a sucrose non-fermenting protein kinase gene, is required for Penicillium digitatum conidiat...
Next Document:  Biocatalysis with immobilized Escherichia coli.