Document Detail


Protein-Losing Gastropathy in Peritoneal Dialysis as a Wolf in Sheep's Clothing: Tc-99m Human Serum Albumin SPECT/CT Diagnosis.
MedLine Citation:
PMID:  22157052     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Protein-losing gastropathy (PLG) is a rare cause of hypoalbuminemia and may be missed in patients with peritoneal dialysis (PD), because PD therapy can lead to hypoalbuminemia and conceal the occurrence of edema. We report a 58-year-old man who underwent PD and presented with unexplained hypoalbuminemia, but lacked gastrointestinal symptoms and edema. PLG was diagnosed by Tc-99m human serum albumin SPECT/CT. The patient's serum albumin level normalized after treatment with a proton-pump inhibitor for 4 months, and his biochemical improvement was also supported by follow-up imaging. Hypoalbuminemia clearly relates to high mortality in PD patients, and Tc-99m human serum albumin SPECT/CT can promote early detection of occult PLG that is masked by PD.
Authors:
Yi-Chun Chen; Yu-Chieh Su; Jainn-Shiun Chiu; Yuh-Feng Wang
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  37     ISSN:  1536-0229     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e16-8     Citation Subset:  IM    
Affiliation:
From the *Division of Nephrology, Department of Internal Medicine, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan; †School of Medicine, Tzu Chi University, Hualien, Taiwan; ‡Division of Hematology-Oncology, Department of Internal Medicine, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan; §Department of Nuclear Medicine, Chang Bing Show Chwan Memorial Hospital, Changhua County, Taiwan; and ¶Department of Nuclear Medicine, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan.
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