| Protein-losing enteropathy caused by gastrointestinal tract-involved Langerhans cell histiocytosis. | |
| | |
MedLine Citation:
|
PMID: 20083519 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Protein-losing enteropathy (PLE) is frequently complicated in patients with gastrointestinal tract-involved Langerhans cell histiocytosis (LCH); however, LCH per se is not generally included in the list of diseases that cause PLE. We report here a case of infantile PLE that presented with continuous diarrhea at the onset of LCH. She was initially diagnosed as having allergic gastroenteropathy and, thus, received intravenous prednisolone, which was thought to have induced immunodeficiency and consequently resulted in life-threatening cytomegalovirus-associated hemophagocytic syndrome and disseminated intravascular coagulation. Because chemotherapy for hemophagocytic syndrome was transiently effective for underlying LCH as well, the diagnosis of LCH was delayed until its recurrence. Gastrointestinal tract-involved LCH, a rare but highly fatal disease, should be considered for infants with refractory gastrointestinal symptoms, especially for those with PLE; endoscopic biopsy is strongly recommended for immediate diagnosis. |
| | |
Authors:
|
Haruko Shima; Takao Takahashi; Hiroyuki Shimada |
Related Documents
:
|
11095569 - Massive pelvic hemangioma in a patient with blue rubber bleb nevus syndrome. 299979 - Noncirrhotic portal hypertension in felty's syndrome. 15829879 - Cowden's syndrome affecting the mouth, gastrointestinal, and central nervous system: a ... 21073049 - Cruveilhier-baumgarten syndrome in a cirrhotic patient taking alcohol with boesenbergia... 1735369 - Acute upper gastrointestinal hemorrhage caused by gallstone impaction in the duodenal b... 11716029 - Idiopathic pneumoperitoneum in a dog. 18796389 - We know that the wasps 'know': cryptic successors to the queen in ropalidia marginata. 17443039 - Occult gastrointestinal bleeding due to acquired von willebrand syndrome in a patient w... 19734379 - The acupuncture treatment for postmenopausal hot flushes (acuflash) study: traditional ... |
Publication Detail:
|
Type: Case Reports; Journal Article; Review Date: 2010-01-18 |
Journal Detail:
|
Title: Pediatrics Volume: 125 ISSN: 1098-4275 ISO Abbreviation: Pediatrics Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-02-03 Completed Date: 2010-03-04 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: United States |
Other Details:
|
Languages: eng Pagination: e426-32 Citation Subset: AIM; IM |
Affiliation:
|
Keio University School of Medicine, Department of Pediatrics, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Colonoscopy Disseminated Intravascular Coagulation / chemically induced Female Gastrointestinal Diseases / complications*, diagnosis, drug therapy Glucocorticoids / adverse effects Histiocytosis, Langerhans-Cell / complications*, diagnosis, drug therapy Humans Infant Prednisolone / adverse effects Protein-Losing Enteropathies / etiology* |
| Chemical | |
Reg. No./Substance:
|
0/Glucocorticoids; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Adoption of Body Mass Index Guidelines for Screening and Counseling In Pediatric Practice.
Next Document: Incidence of Fractures Among Children With Burns With Concern Regarding Abuse.