| Protective and ultra-protective ventilation: using pumpless interventional lung assist (iLA). | |
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MedLine Citation:
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PMID: 21540810 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Acute lung failure is associated with high mortality and usually requires mechanical ventilation to ensure adequate gas exchange. However, mechanical ventilation itself can be associated with major complications and can aggravate pre-existing lung disease, thus contributing to morbidity and mortality. Extracorporeal gas exchange is increasingly used when conventional mechanical ventilation has failed. In contrast to veno-venous extracorporeal membrane oxygenation (ECMO), pumpless extracorporeal interventional lung assist (iLA) is applied via an arterio-venous bypass into which a gas exchange membrane is integrated. iLA allows for efficient carbon dioxide removal, which allows for a significant reduction in ventilator settings. iLA may be a useful tool in protective or even 'ultraprotective' ventilation, enabling the application of very low tidal volumes in patients with acute respiratory failure of different etiologies. This article reviews the current status and the potential role of interventional (pumpless) lung-assist iLA within the context of lung-protective ventilation strategies. |
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Authors:
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O Moerer; M Quintel |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Minerva anestesiologica Volume: 77 ISSN: 1827-1596 ISO Abbreviation: Minerva Anestesiol Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-05-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375272 Medline TA: Minerva Anestesiol Country: Italy |
Other Details:
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Languages: eng Pagination: 537-44 Citation Subset: IM |
Affiliation:
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Department Anaesthesiology, Emergency and Critical Care Medicine, Georg-August-University of Göttingen, Göttingen, Germany - omoerer@gwdg.de. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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