Document Detail

Protective effect of oral Lactobacilli in pathogenesis of chronic periodontitis.
MedLine Citation:
PMID:  22314572     Owner:  NLM     Status:  MEDLINE    
CONCLUSIONS: development of CP is linked to persistent excessive cytokine response of Th17 cells, the intensity of which may affect clinical course of the disease; in parallel, H(2)O(2)-producing oral lactobacilli may prevent against progression of CP, most probably reducing secretory activity of Th17 cells and restricting growth of periodontopathogens.
A K Szkaradkiewicz; T M Karpinski; A Zeidler; M Wyganowska-Swiatkowska; Andrzej Szkaradkiewicz
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society     Volume:  62     ISSN:  1899-1505     ISO Abbreviation:  J. Physiol. Pharmacol.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-02-08     Completed Date:  2012-09-26     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  9114501     Medline TA:  J Physiol Pharmacol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  685-9     Citation Subset:  IM    
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MeSH Terms
Administration, Oral
Chronic Periodontitis / microbiology*,  pathology,  prevention & control*
Disease Progression*
Interleukin-17 / metabolism
Lactobacillus / isolation & purification*,  metabolism
Th17 Cells / metabolism
Tumor Necrosis Factor-alpha / metabolism
Reg. No./Substance:
0/Interleukin-17; 0/Tumor Necrosis Factor-alpha

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