Document Detail


Protective effect of hyaluronidase after long-term aortic cross-clamping: initial experimental observations.
MedLine Citation:
PMID:  7362328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This work studies the effect of hyaluronidase on myocardium subjected to long-term aortic cross-clamping (three hours) and moderate hypothermia (28 degrees C). Animals receiving hyaluronidase (1,00o U per liter) through the root of the aorta with a procaine-potassium chloride-lasmalyte cardioplegic solution showed better functional, electrical, and morphological response than the untreated animals. These findings, although preliminary, appear to be promising for potential clinical application.
Authors:
D Vij; L H Toledo-Pereyra; D J Magilligan; F M Jara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  29     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1980 Apr 
Date Detail:
Created Date:  1980-05-30     Completed Date:  1980-05-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  346-50     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cardiopulmonary Bypass*
Coronary Circulation / drug effects*
Dogs
Electrocardiography
Female
Hemodynamics / drug effects
Hyaluronoglucosaminidase / pharmacology*
Male
Myocardium / pathology
Chemical
Reg. No./Substance:
EC 3.2.1.35/Hyaluronoglucosaminidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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