Document Detail


Protection of mice against vaccinia virus by bacterial infection and sustained stimulation with specific bacterial antigens.
MedLine Citation:
PMID:  4632135     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In these experiments, mice which have a strong delayed-type hypersensitivity to mycobacteria were found, when elicited with old tuberculin, to be more resistant to intravenous vaccinia virus challenge than controls. This was manifest as protection from killing when large amounts of virus were injected, or as significantly less tail swelling and damage as well as lower titers of infectious virus when a lesser inoculum was used. Preliminary experiments indicate that animals sensitized with Staphylococcus aureus and elicited with phage lysate of staphylococcus are also more resistant to vaccinia infection.
Authors:
E G Allen; S Mudd
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Infection and immunity     Volume:  7     ISSN:  0019-9567     ISO Abbreviation:  Infect. Immun.     Publication Date:  1973 Jan 
Date Detail:
Created Date:  1973-05-02     Completed Date:  1973-05-02     Revised Date:  2010-09-10    
Medline Journal Info:
Nlm Unique ID:  0246127     Medline TA:  Infect Immun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  62-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Antigens, Bacterial*
Bacteriophages / immunology
Mice
Mycobacterium tuberculosis / immunology
Staphylococcus / immunology
Tail
Tuberculin Test
Vaccinia / immunology*
Vaccinia virus / immunology*,  pathogenicity
Chemical
Reg. No./Substance:
0/Antigens, Bacterial
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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