Document Detail

Protection by flavanol-rich foods against vascular dysfunction and oxidative damage: 27th Hohenheim Consensus Conference.
MedLine Citation:
PMID:  22516731     Owner:  NLM     Status:  MEDLINE    
Criteria for assessing the purported protection by flavanol-rich foods against vascular dysfunction and oxidative damage to biomolecules was the subject of the 27th Hohenheim Consensus Conference held on July 11, 2011. State-of-the-art evidence was put into perspective, focusing on several questions that were followed by a consensus answer. Among the topics addressed were the major sources of flavanols in the human diet, the bioavailability of flavanols, biomarkers for "health benefit," and the biological function of flavanols. Consensus was reached on these topics. No conclusion was reached on the design of randomized, controlled trials for substantiation of health claims for flavanol-rich foods as to the necessity of a study arm with an isolated pharmacologically active compound, e.g., (-)-epicatechin.
Helmut Sies; Peter C H Hollman; Tilman Grune; Wilhelm Stahl; Hans K Biesalski; Gary Williamson
Publication Detail:
Type:  Consensus Development Conference; Journal Article     Date:  2012-03-01
Journal Detail:
Title:  Advances in nutrition (Bethesda, Md.)     Volume:  3     ISSN:  2156-5376     ISO Abbreviation:  Adv Nutr     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-04-20     Completed Date:  2012-09-18     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101540874     Medline TA:  Adv Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  217-21     Citation Subset:  IM    
Institute for Biochemistry and Molecular Biology I, Düsseldorf, Germany.
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MeSH Terms
Biological Availability
Biological Markers / analysis
Flavonoids / pharmacokinetics,  pharmacology*
Oxidative Stress / drug effects*
Vascular Diseases / prevention & control*
Reg. No./Substance:
0/Biological Markers; 0/Flavonoids

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