Document Detail

Protection of Escherichia coli from the lethal effect of colicins by high osmotic pressure.
MedLine Citation:
PMID:  5335904     Owner:  NLM     Status:  MEDLINE    
The sensitivity of Escherichia coli to the lethal effect of colicin E(2) was reduced by elevation of osmotic pressure of the incubation medium. Optimal protection of the cells from the lethal effect of colicin E(2) was achieved with 0.6 to 0.8 m NaCl or with 0.8 m sucrose containing 0.01 m MgSO(4). Under such conditions, the degradation of deoxyribonucleic acid caused by colicin E(2) was also suppressed markedly. It was concluded that a high concentration of sucrose with Mg(++) might prevent the action of the adsorbed colicin E(2). A similar protection was observed against the lethal effect of colicin K.
R Beppu; K Arima
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of bacteriology     Volume:  93     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1967 Jan 
Date Detail:
Created Date:  1967-05-10     Completed Date:  1967-05-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  80-5     Citation Subset:  IM    
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MeSH Terms
Carbon Isotopes
Colicins / pharmacology*
DNA, Bacterial / metabolism
Escherichia coli / drug effects*
Magnesium Sulfate / pharmacology
Phosphorus Isotopes
Sodium Chloride / pharmacology*
Sucrose / pharmacology*
Reg. No./Substance:
0/Carbon Isotopes; 0/Colicins; 0/DNA, Bacterial; 0/Phosphorus Isotopes; 57-50-1/Sucrose; 7487-88-9/Magnesium Sulfate; 7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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