Document Detail

Prosthodontic treatment during active osteonecrosis related to radiation and bisphosphonate therapy: a clinical report.
MedLine Citation:
PMID:  16872925     Owner:  NLM     Status:  MEDLINE    
Osteonecrosis of the jaws following the use of bisphosphonate drugs has been reported in the literature. Presently, there is limited evidence to establish guidelines for the prosthodontic management of patients with active osteonecrosis, a history of osteonecrosis, or medical history of using these medications. This clinical report reviews the current literature regarding bisphosphonate use, and reports the prosthodontic treatment of an edentulous patient with active osteonecrosis who had a history of oral bisphosphonate use and jaw irradiation.
Mark Marunick; Sara Gordon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of prosthetic dentistry     Volume:  96     ISSN:  0022-3913     ISO Abbreviation:  J Prosthet Dent     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-28     Completed Date:  2006-10-24     Revised Date:  2009-02-19    
Medline Journal Info:
Nlm Unique ID:  0376364     Medline TA:  J Prosthet Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7-12     Citation Subset:  D; IM    
Department of Otolaryngology-Head and Neck Surgery, Wayne State University School of Medicine, 4201 St. Antoine, UHC-5G, Detroit, MI 48201, USA.
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MeSH Terms
Alendronate / adverse effects*
Bone Density Conservation Agents / adverse effects*
Carcinoma, Squamous Cell / radiotherapy
Cranial Irradiation / adverse effects*
Denture, Complete, Upper*
Mandibular Diseases / complications,  etiology*,  surgery
Middle Aged
Mouth Neoplasms / radiotherapy
Mouth, Edentulous / complications,  rehabilitation*
Osteonecrosis / complications,  etiology*,  surgery
Osteoradionecrosis / complications,  etiology,  surgery
Reg. No./Substance:
0/Bone Density Conservation Agents; 66376-36-1/Alendronate
Comment In:
J Prosthet Dent. 2008 Oct;100(4):249   [PMID:  18922251 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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