Document Detail

Prosthetic valve selection for a pulsatile LVAD.
MedLine Citation:
PMID:  10115616     Owner:  NLM     Status:  MEDLINE    
During the final development of a unique Magnetically Actuated Left Ventricle Assist Device (MALVAD), three of the most widely used clinical prosthetic valves were evaluated to determine their suitability for the stringent requirements for LVAD use, in both the inflow and outflow positions. The three valves (St. Jude Medical-SJM; Medtronic Hall-MH; Bjork-Shiley Convex-Concave-BSCC), with lumen size of 25 mm, were tested in the same appropriate mock loop to the following set of hydraulic parameters: 1) after-load systemic pressure = constant 100 mmHg; 2) preload pressure ranged from 3 mm to 18 mmHg; 3) beat rate ranged from 60 bpm to 80 bpm. Pump actuator power was held constant, correspondent with specific bpm rate, for all valves tested. Results from a series of 10 bench tests per valve showed that the SJM was significantly better, on a statistical basis, than both the MH and BSCC valves, at fill pressures of 5 mmHg. At 10-mm fill pressure, however, the statistical flow rates for both the SJM and the MH valves were significantly superior to the BSCC valve, so that the BSCC valve was classified as a marginal candidate for LVAD use. The SJM and MH valves had bench test flow-rate values whose numerical difference was too small to serve conclusively as an arbitrary basis for valve choice. Because of this, the two valves were further evaluated in terms of two widely recognized, mandatory LVAD valve design criteria: (1) comparative mechanical ruggedness, and (2) relative ease and simplicity of LVAD design inclusion.(ABSTRACT TRUNCATED AT 250 WORDS)
S G Kovacs; P P McKeown
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of clinical engineering     Volume:  16     ISSN:  0363-8855     ISO Abbreviation:  J Clin Eng     Publication Date:    1991 Nov-Dec
Date Detail:
Created Date:  1992-02-12     Completed Date:  1992-02-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7703941     Medline TA:  J Clin Eng     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  515-9     Citation Subset:  H    
College of Medicine, University of South Florida, Tampa.
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MeSH Terms
Blood Flow Velocity
Equipment Design / standards
Heart Valve Prosthesis / standards*
Heart-Assist Devices / standards*
Technology Assessment, Biomedical*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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