Document Detail

Prosthetic valve endocarditis caused by Legionella pneumophila.
MedLine Citation:
PMID:  6703545     Owner:  NLM     Status:  MEDLINE    
Prosthetic valve endocarditis due to Legionella pneumophila occurred in a woman who had aortic and mitral valve replacements with porcine xenografts. During surgery for persistent fever and aortic regurgitation due to presumed endocarditis, she had vegetations involving both the aortic and mitral valve prostheses with a circumferential abscess of the aortic annulus. Cultures, Dieterle stain, and direct fluorescent antibody stain of valve tissue, and subsequent measurements of serum antibody levels confirmed L. pneumophila as the infecting organism. This infection occurred in the absence of pneumonia. Legionella pneumophila must be considered a potential cause of culture-negative prosthetic valve endocarditis and should be sought in appropriate clinical circumstances.
R E McCabe; J C Baldwin; C A McGregor; D C Miller; K L Vosti
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of internal medicine     Volume:  100     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1984 Apr 
Date Detail:
Created Date:  1984-04-12     Completed Date:  1984-04-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  525-7     Citation Subset:  AIM; IM    
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MeSH Terms
Aortic Valve
Bacterial Infections / drug therapy*
Drug Therapy, Combination
Endocarditis, Bacterial / microbiology*
Erythromycin / therapeutic use
Heart Valve Prosthesis / adverse effects*
Middle Aged
Mitral Valve
Rifampin / therapeutic use
Reg. No./Substance:
114-07-8/Erythromycin; 13292-46-1/Rifampin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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