Document Detail

Prosthesis endocarditis: treatment of a case occurring five years after a Rastelli-Ross operation.
MedLine Citation:
PMID:  132578     Owner:  NLM     Status:  MEDLINE    
A severe staphylococcal septicemia originating from an unknown focus occurred in a 17-year-old patient who had undergone a Rastelli-Ross operation 5 years earlier. The clinical course was complicated by extensive bilateral pneumonia, diffuse intravascular coagulation, and glomerulonephritis. After 4 weeks of intensive conservative treatment, including a daily regimen of 16 Gm. of cloxacillin, the patient was operated upon for a rapidly progressive false aneurysm, which had resulted from dehiscence of the anastomosis between the prosthesis and ventricle. The excised prosthesis proved to be sterile. The postoperative course was uneventful. Cloxacillin treatment was continued for 6 months, initially parenterally and later orally. After discontinuation of therapy, no signs of infection have occurred. Right-sided intracardiac or intravascular prosthetic material may be particularly susceptible to infections originating from the body surface.
J Thompson; T Dirksen; M Nubé; A G Brom
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of thoracic and cardiovascular surgery     Volume:  72     ISSN:  0022-5223     ISO Abbreviation:  J. Thorac. Cardiovasc. Surg.     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-09-01     Completed Date:  1976-09-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376343     Medline TA:  J Thorac Cardiovasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  28-32     Citation Subset:  AIM; IM    
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MeSH Terms
Aneurysm, Infected / surgery
Blood Vessel Prosthesis / adverse effects*
Cloxacillin / therapeutic use
Endocarditis, Bacterial / complications,  drug therapy*,  radiography
Heart Aneurysm / surgery
Penicillin Resistance
Pneumonia, Staphylococcal / radiography
Polyethylene Terephthalates / adverse effects
Sepsis / drug therapy
Staphylococcal Infections / complications,  drug therapy*,  radiography
Tetralogy of Fallot / surgery*
Reg. No./Substance:
0/Polyethylene Terephthalates; 61-72-3/Cloxacillin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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