Document Detail


Prostatic aspergillosis in a heart transplant recipient: case report and review.
MedLine Citation:
PMID:  19481027     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study we report the first case of invasive prostatic aspergillosis (IPRA) in a heart recipient with post-transplantation antibody deficiency, and review the other 11 cases described in the medical literature. Seven patients were immunocompromised and 6 had dissemination to other sites. Examination of the prostate usually revealed enlargement, with or without nodular lesions. Transrectal ultrasonography or computed tomography scan can provide the diagnosis, although this should be confirmed with biopsy and culture of the lesion. Urine culture can be negative and treatment should include long-term systemic anti-fungal therapy and, in most cases, prostatectomy.
Authors:
Maricela Valerio; Ana Fernandez-Cruz; Juan Fernández-Yañez; Jesús Palomo; Jesús Guinea; Ramón Durán; Elisabeth Sarmiento; Javier Carbone; Emilio Bouza; Patricia Muñoz
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-05-05
Journal Detail:
Title:  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation     Volume:  28     ISSN:  1557-3117     ISO Abbreviation:  J. Heart Lung Transplant.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-01     Completed Date:  2009-09-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102703     Medline TA:  J Heart Lung Transplant     Country:  United States    
Other Details:
Languages:  eng     Pagination:  638-46     Citation Subset:  IM    
Affiliation:
Department of Clinical Microbiology-Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
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MeSH Terms
Descriptor/Qualifier:
Aged
Antifungal Agents / therapeutic use
Aspergillosis / diagnosis*,  drug therapy
Biopsy
Heart Transplantation / immunology*
Humans
Immunocompromised Host*
Male
Opportunistic Infections / diagnosis,  microbiology,  therapy
Prostate / microbiology*,  pathology,  ultrasonography
Prostatectomy
Prostatic Diseases / diagnosis*,  microbiology*,  therapy
Chemical
Reg. No./Substance:
0/Antifungal Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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