Document Detail

Prostatic abscess in a pediatric patient with chronic granulomatous disease: report of a unique case and review of the literature.
MedLine Citation:
PMID:  22325401     Owner:  NLM     Status:  MEDLINE    
Chronic granulomatous disease (CGD) is a rare hereditary disease in which phagocytes have difficulty forming the superoxide radical required to kill certain pathogens. Individuals with CGD are susceptible to a specific set of infections and granulomatous lesions. We present the case of a 15-year-old boy with X-linked CGD who presented with unremitting cough and fevers. He had a left-sided pneumonia that persisted despite home intravenous antibiotics. He was admitted to an outside facility for bronchoalveolar lavage to obtain cultures and polymerase chain reaction. Computed tomography of chest, abdomen, and pelvis was done for baseline evaluation of extent of disease. Computed tomography revealed a fluid collection in the prostatic fossa, later determined to be a prostatic abscess. To our knowledge, this is the first reported case of a prostatic abscess in a pediatric patient with CGD.
Nnenaya Q Agochukwu; Ardeshir R Rastinehad; Lee A Richter; Stephanie Barak; Christa S Zerbe; Steven M Holland; Peter A Pinto
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  47     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-02-13     Completed Date:  2012-06-28     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  400-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1210, USA.
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MeSH Terms
Abscess / drug therapy,  etiology*,  radiography,  surgery
Anti-Bacterial Agents / therapeutic use
Burkholderia Infections / complications,  drug therapy
Burkholderia cepacia / isolation & purification
Candida albicans / isolation & purification
Drug Resistance, Multiple, Bacterial
Fever / etiology
Granulomatous Disease, Chronic / complications*
Immunocompromised Host
Incidental Findings
Pneumonia, Bacterial / complications,  radiography
Prostatitis / drug therapy,  etiology*,  radiography,  surgery
Tomography, X-Ray Computed
Transurethral Resection of Prostate
Grant Support
Z01 BC011023-01/BC/NCI NIH HHS
Reg. No./Substance:
0/Anti-Bacterial Agents

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