Document Detail


Prostate blood flow characteristics in the chronic prostatitis/pelvic pain syndrome.
MedLine Citation:
PMID:  10737481     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: We determine whether the chronic prostatitis/pelvic pain syndrome is associated with abnormal prostate blood flow. MATERIALS AND METHODS: We used color Doppler ultrasonography to examine 53 patients with inflammation, 80 men without inflammation and 22 healthy controls. Images were recorded and scored using standardized criteria to characterize the degree and distribution of prostatic vascularity. RESULTS: Flow was observed to the entire prostatic capsule in 77% of patients but only 18% of controls (p<0.0001). Parenchymal flow was evaluated using several criteria. On a 2-point scale flow was classified as grade 2 in 74% of patients compared to 27% of controls (p<0.0001). Similar findings were noted on a Doppler spot scale, with flow classified as grade 2 in 47% of patients compared to 14% of controls (p<0.004). Patients also had more parenchymal Doppler spots than controls (p<0.01). Diffuse blood flow throughout the prostatic parenchyma was observed in 63% of patients compared to 36% of controls (p<0.03). There was no significant difference in the amount or distribution of blood flow in patients with and without inflammation. CONCLUSIONS: The chronic prostatitis/pelvic pain syndrome was associated with increased blood flow to the prostatic capsule and diffuse flow throughout the prostatic parenchyma. Despite technical limitations, color Doppler ultrasonography may provide objective documentation of prostate blood flow abnormalities in patients with this syndrome.
Authors:
I R Cho; T S Keener; H V Nghiem; T Winter; J N Krieger
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of urology     Volume:  163     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-04-24     Completed Date:  2000-04-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1130-3     Citation Subset:  AIM; IM    
Affiliation:
Department of Urology, University of Washington School of Medicine, Seattle, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Chronic Disease
Humans
Male
Middle Aged
Pelvic Pain / physiopathology*,  ultrasonography
Prostate / blood supply*,  ultrasonography
Prostatitis / physiopathology*,  ultrasonography
Regional Blood Flow
Syndrome
Ultrasonography, Doppler, Color
Grant Support
ID/Acronym/Agency:
R01 DK38955/DK/NIDDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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