Document Detail

Prostaglandins and sex steroids from corpora lutea of pregnant mares. In vitro studies.
MedLine Citation:
PMID:  7878194     Owner:  NLM     Status:  MEDLINE    
To delineate endocrine mechanisms regulating equine luteal function and the possible functional differences between one month and three month corpora lutea of pregnancy (CL), the in vitro basal releases of prostaglandin F (PGF), prostaglandin E2 (PGE2), progesterone, and 17 beta-estradiol by one and three month CL of pregnant mares were evaluated. In addition, the in vitro effects of PGF2 alpha PGE2, progesterone and 17 beta-estradiol on synthesis of prostaglandins (PGs) and sex steroids were studied. PGF, PGE2, and 17 beta-estradiol secretion was higher in one month than in three month CL, while progesterone was secreted similarly by both types of CL. PGE2 treatment decreased 17 beta-estradiol in one month CL; progesterone increased PGE2 in one and three month CL; 17 beta-estradiol increased PGE2 in one month CL. This study suggests that, in one month CL, PGE2 production could be regulated by progesterone and 17 beta-estradiol, while, in three month CL, this prostaglandin seems to be under the control of progesterone alone.
A Gobbetti; M Zerani; F Vannucci; R Marini
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Prostaglandins     Volume:  48     ISSN:  0090-6980     ISO Abbreviation:  Prostaglandins     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1995-03-31     Completed Date:  1995-03-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0320271     Medline TA:  Prostaglandins     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  262-72     Citation Subset:  IM    
Department of Molecular, Cellular and Animal Biology, University of Camerino, Italy.
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MeSH Terms
Corpus Luteum / secretion*
Dinoprostone / secretion*
Estradiol / secretion*
Evaluation Studies as Topic
Horses / physiology*
Progesterone / secretion*
Prostaglandins F / secretion*
Reg. No./Substance:
0/Prostaglandins F; 363-24-6/Dinoprostone; 50-28-2/Estradiol; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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