Document Detail


Prostaglandins and sex steroids from corpora lutea of pregnant mares. In vitro studies.
MedLine Citation:
PMID:  7878194     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To delineate endocrine mechanisms regulating equine luteal function and the possible functional differences between one month and three month corpora lutea of pregnancy (CL), the in vitro basal releases of prostaglandin F (PGF), prostaglandin E2 (PGE2), progesterone, and 17 beta-estradiol by one and three month CL of pregnant mares were evaluated. In addition, the in vitro effects of PGF2 alpha PGE2, progesterone and 17 beta-estradiol on synthesis of prostaglandins (PGs) and sex steroids were studied. PGF, PGE2, and 17 beta-estradiol secretion was higher in one month than in three month CL, while progesterone was secreted similarly by both types of CL. PGE2 treatment decreased 17 beta-estradiol in one month CL; progesterone increased PGE2 in one and three month CL; 17 beta-estradiol increased PGE2 in one month CL. This study suggests that, in one month CL, PGE2 production could be regulated by progesterone and 17 beta-estradiol, while, in three month CL, this prostaglandin seems to be under the control of progesterone alone.
Authors:
A Gobbetti; M Zerani; F Vannucci; R Marini
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Prostaglandins     Volume:  48     ISSN:  0090-6980     ISO Abbreviation:  Prostaglandins     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1995-03-31     Completed Date:  1995-03-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0320271     Medline TA:  Prostaglandins     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  262-72     Citation Subset:  IM    
Affiliation:
Department of Molecular, Cellular and Animal Biology, University of Camerino, Italy.
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MeSH Terms
Descriptor/Qualifier:
Animals
Corpus Luteum / secretion*
Dinoprostone / secretion*
Estradiol / secretion*
Evaluation Studies as Topic
Female
Horses / physiology*
Pregnancy
Progesterone / secretion*
Prostaglandins F / secretion*
Chemical
Reg. No./Substance:
0/Prostaglandins F; 363-24-6/Dinoprostone; 50-28-2/Estradiol; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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